Microfluidics Reaction Technology
In addition to top-down uniform particle size reduction to the nano-level, Microfluidics Reaction TechnologyTM (MRT) combines an impinging jet processor with application and process development to create nanoparticles bottom-up. Using continuous crystallization, chemical reactions and process intensification, MRT typically enables pharmaceutical, energy and chemical companies to achieve particle sizes impossible with any other method. Applications of MRT:
- Continuous crystallization
- Efficient nanoencapsulation
- Chemical reactions
- Process intensification
Proven Processing Results
MRT has been named a Nano50 Award winner due to its unique capabilities to produce superior particle size distributions efficiently for a number of APIs:
| Active Pharmaceutical Ingredient |
MRT Crystallization
1 pass (nm)
|
Beaker Crystallization (nm) |
Top-down Particle Size Reduction
25 passes (nm)
|
| Norfloxacin |
180 |
3,000 x 1,000,000 |
428 |
| Oxcarbazepine |
767 |
5,000 x 20,000 |
1,200 |
| Loratadine |
90-332 |
|
|
Azithromycin
MRT crystallization achieved a z-average of 82 nm (ranging as small as 54 nm) with narrow distribuion.
Learn More
Contact us to begin a discussion on whether MRT can solve your formulation and product challenges.
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