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Nanoencapsulation

Microfluidizer® Technology Provides a Competitive Edge

Nanoencapsulation Techniques

Nanoencapsulation techniques using nanoemulsions, liposomes and polymers are primarily used in the pharmaceutical, nutraceutical/food and cosmetic industries. Nanoencapsulation in food, drug and other applications enables companies to achieve:

  • Time release of actives (e.g., small and large molecule drugs, pesticides/herbicides)
  • Targeted drug delivery
  • Odor/flavor masking (e.g., fish oil)
  • Protection (e.g., vitamins, DNA, tattoo ink, fish oil) 

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Advantages of Microfluidizer Technology for Nanoencapsulation

Customers using Microfluidizer® processor technology for nanoencapsulation applications enjoy competitive differentiation for their products and processes:

  • Smaller particle sizes
  • Uniform particle size distribution
  • Efficient encapsulation rates
  • Effective cooling
  • Precise shear
  • Controlled mixing intensity of reactant streams
  • Ease of use, cleaning and maintenance
  • Scaleup guaranteed

Proven Drug Nanoencapsulation Results

Nanoemulsions

Fish oil contains Omega-3 fatty acid, an essential nutrient. Encapsulating the fish oil using a nanoemulsion substantially reduces its undesirable taste and protects the oil from oxidation.

Liposomes

In the example below, 0.1% plasmid DNA is encapsulated inside a Palmitoyl oleoyl phophatidyl choline liposome. DNA remains.

Polymers

Microfluidizer technology is ideally suited for applications requiring highly efficient polymer encapsulation.

BeforeAfter

 

PolydispersityDNA Encapsulation in a Liposome
Chart of DNA Encapsulation in a Liposome

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