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Liposomes

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  • Liposomes are artificially created, microscopic, spherical structures that take a page from na-ture to exploit certain useful properties found in living cells. Their design enables them to excel at the targeted delivery of payloads, such as chemotherapeutic drugs delivered to tumor cells. Their defining characteristic is a lipid bilayer, consisting of phospholipids, such as phosphatidyl-choline, which encase one or...
  • Cancer is the second-leading cause of mortality worldwide, and the number of annual deaths continues to rise. From 2005 to 2015, for instance, cancer cases rose by 33 percent in a majority of countries. While some of this troubling increase may be attributed to overall growth in population and aging, it’s clear that the need has never been greater for effective chemotherapy drugs and other cancer therapies....
  • Pharmaceutical industry prognosticators recognize that liposomes will play an increasingly important role in the development of new drugs for the foreseeable future, due to the unique drug-delivery advantages these designer entities offer. With a heterogenous bilayer encapsulating an aqueous interior core, liposomes are ideal vesicles for the delivery of pharmacological payloads consisting of a hydrophilic compound...
  • Since the eradication of smallpox nearly four decades ago, the quest to develop effective vaccines for any number of other diseases has benefitted from significant advances in medical science and technology. In subsequent years, various methods of vaccine delivery have been pioneered. Modern vaccine development goals include improved efficacy, reduced risk, enhanced safety and better stability of vaccines; as well...